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Understanding Squamous Cell Carcinoma- symptoms, signs and treatment

What is Squamous Cell Carcinoma?

Squamous cell carcinoma (SCC) is a type of skin cancer that develops in the squamous cells, which are flat cells found in the outer layer of the skin, known as the epidermis. This condition is becoming increasingly common in India, making it crucial for people to understand its causes, symptoms, and treatment options.

The Role of Squamous Cells

Squamous cells play a vital role in our body’s protective barrier. They are found not only in the skin but also in the lining of hollow organs and the respiratory and digestive tracts. When these cells undergo abnormal changes and grow uncontrollably, they can lead to the formation of squamous cell carcinoma.

Causes and Risk Factors

Understanding the causes and risk factors of squamous cell carcinoma is essential for prevention and early detection. Let’s explore some of the primary factors that contribute to the development of this skin cancer:

Sun Exposure

In India, where sunshine is abundant throughout the year, prolonged exposure to ultraviolet (UV) radiation from the sun is the leading cause of squamous cell carcinoma. The intense sunlight, especially during peak hours, can damage the DNA in skin cells, leading to mutations that may result in cancer.

Fair Skin

People with lighter skin tones are more susceptible to squamous cell carcinoma. However, it’s important to note that individuals with darker skin can also develop this condition, particularly in areas less exposed to the sun.

Age and Gender

The risk of developing squamous cell carcinoma increases with age. Men are more likely to develop this type of skin cancer, possibly due to higher sun exposure in outdoor occupations.

Weakened Immune System

Individuals with compromised immune systems, such as those undergoing organ transplants or living with HIV/AIDS, are at a higher risk of developing squamous cell carcinoma.

Genetic Factors

Certain genetic conditions, like xeroderma pigmentosum, can increase the likelihood of developing squamous cell carcinoma.

Symptoms and Signs

Recognizing the symptoms of squamous cell carcinoma is crucial for early detection and treatment. Here are some common signs to watch out for:

  • A firm, red nodule on the skin
  • A flat sore with a scaly crust
  • A new sore or raised area on an old scar or ulcer
  • A rough, scaly patch on the lip that may evolve into an open sore
  • A red, raised patch or irritated area on the genitals

Remember: Any persistent change in your skin should be evaluated by a healthcare professional.

Diagnosis of Squamous Cell Carcinoma

If you notice any suspicious changes in your skin, it’s essential to consult a dermatologist. The diagnosis of squamous cell carcinoma typically involves the following steps:

Physical Examination

The doctor will carefully examine the affected area and may use a dermatoscope, a special magnifying instrument, to get a closer look at the skin lesion.

Skin Biopsy

A skin biopsy is usually necessary to confirm the diagnosis. This involves removing a small sample of the suspicious tissue and examining it under a microscope. There are several types of skin biopsies:

  • Shave biopsy: The doctor shaves off the top layers of skin
  • Punch biopsy: A small, circular tool is used to remove a deeper sample of skin
  • Incisional biopsy: A small part of the growth is removed
  • Excisional biopsy: The entire growth is removed

Imaging Tests

In some cases, especially if there’s concern that the cancer may have spread, the doctor might recommend imaging tests such as X-rays, CT scans, or MRI scans.

Treatment Options

The treatment for squamous cell carcinoma depends on various factors, including the size, location, and depth of the tumor, as well as the patient’s overall health. Here are some common treatment options:

Surgical Procedures

  • Excisional surgery: The cancerous tissue and some surrounding healthy skin are removed.
  • Mohs surgery: This precise technique removes the cancer layer by layer, preserving as much healthy skin as possible.
  • Curettage and electrodesiccation: The tumor is scraped away, and the base is treated with an electric needle to destroy any remaining cancer cells.

Radiation Therapy

For squamous cell carcinomas that can’t be fully removed with surgery or for patients who can’t undergo surgery, radiation therapy might be recommended. This treatment uses high-energy beams to kill cancer cells.

Cryosurgery

This technique involves freezing the cancer cells with liquid nitrogen. It’s typically used for small, well-defined tumors.

Photodynamic Therapy

This treatment combines light-sensitive drugs with light exposure to destroy cancer cells. It’s often used for superficial squamous cell carcinomas.

Topical Medications

For very superficial cancers, topical drugs like fluorouracil or imiquimod may be prescribed. These medications are applied directly to the skin to kill cancer cells.

Prevention Strategies

While not all cases of squamous cell carcinoma can be prevented, there are several steps you can take to reduce your risk:

Sun Protection

  • Use a broad-spectrum sunscreen with an SPF of at least 30
  • Wear protective clothing, including long-sleeved shirts and wide-brimmed hats
  • Seek shade, especially during peak sunlight hours (10 am to 4 pm)

Regular Skin Checks

Perform self-examinations of your skin monthly and schedule annual check-ups with a dermatologist.

Avoid Tanning Beds

Tanning beds emit harmful UV radiation and significantly increase the risk of skin cancer.

Healthy Lifestyle

Maintain a balanced diet rich in antioxidants and stay hydrated to support overall skin health.

Living with Squamous Cell Carcinoma

A diagnosis of squamous cell carcinoma can be challenging, but with proper care and support, most patients have a positive outlook. Here are some tips for living with this condition:

Follow-up Care

Regular follow-up appointments with your dermatologist are crucial to monitor for recurrence or new skin cancers.

Emotional Support

Don’t hesitate to seek emotional support from friends, family, or support groups. Many people find comfort in connecting with others who have similar experiences.

Lifestyle Adjustments

You may need to make some changes to your daily routine, such as being more vigilant about sun protection or adjusting outdoor activities.

Squamous Cell Carcinoma in India: A Growing Concern

In recent years, there has been an increase in the incidence of squamous cell carcinoma in India. This rise can be attributed to several factors:

  • Increased awareness and improved diagnostic techniques
  • Changes in lifestyle and increased sun exposure
  • Environmental factors, including pollution

It’s crucial for Indian people to be aware of this growing health concern and take proactive steps to protect their skin.

Conclusion

Squamous cell carcinoma is a serious but treatable form of skin cancer. By understanding its causes, recognizing its symptoms, and taking preventive measures, you can significantly reduce your risk. Remember, early detection is key to successful treatment.

If you notice any unusual changes in your skin, don’t hesitate to consult a healthcare professional. With proper care and attention, you can maintain healthy skin and reduce your risk of squamous cell carcinoma.

Stay informed, stay protected, and prioritize your skin health. Your skin is your body’s largest organ – treat it with the care it deserves.

Dr Sagar Kajbaje

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